I recently came across
3 new studies that examined the safety and efficacy of intermittent fasting as
a weight loss strategy. I thought a quick summary of these articles would make
for a nice post since I get so many questions on fasting from my clients.
Study #1
In this first study, 81 overweight subjects were randomized to one of two
groups. One group consumed a normal calorie reduced diet. The other consumed
the same diet, but restricted eating to a 10 hour window. After 39 weeks, there
were no differences in the amount of weight lost. In other words, intermittent
fasting resulted in no more weight loss than eating your meals spaced out
normally (Reference 1).
Study #2
In this cross-sectional
study, 1,047 older adults had their diets assessed by means of a food frequency
questionnaire. Blood was also taken and cardiovascular disease biomarkers were
measured. Longer fasting time was associated with lower HDL cholesterol, higher
potassium levels and lower chloride levels. Although many believe that fasting
improves cardiovascular disease risk factors, these are mildly detrimental
associations (Reference 2).
Study #3
In this trial, 139
obese subjects were randomized to one of two groups:
-A time restricted
eating group that limited food consumption to the hours of 8:00 AM and 4:00 PM.
-A normal calorie
restricted group.
Each group had a
goal of 1200 calories per day for the women and 1500 calories for the men. After
12 months, there was no significant difference in weight loss between the two
groups (Reference 3).
Conclusions And Recommendations
The evidence is really starting to mount that intermittent fasting is not
an effective or even a healthy way to lose weight.
These studies, and other included in previous blog posts have shown that:
-Fasting is no more effective for weight loss than a more conventional, 3
meal a day approach.
-Fasting can have a negative impact on HDL and LDL cholesterol.
-Fasting can have a negative impact on blood glucose regulation.
-Fasting can have a negative impact on inflammation.
-Fasting increases hunger.
-Fasting has been shown to decrease metabolic rate, so you burn fewer calories
in a day that you fast.
-Fasting has been shown to lower levels of physical activity.
-Fasting has been shown to have a negative impact on sleep.
-It is harder to adhere to a fasting protocol than a 3 meal a day plan.
-Fasting may lead to an increase in muscle loss.
If you want to see some of the research quoted above, click on this link.
From my viewpoint, enough research has accumulated to conclude that
fasting is not the way to go if you want to lose weight, reduce your risk of chronic
disease and/or improve your quality of life.
Three, spaced out meals a day is the best option to help you lose weight,
keep your blood sugar stable for all day energy and will allow you enough
eating opportunities to make sure you are getting adequate fiber, vitamins, minerals
and phytochemicals.
References
1) Thomas EA, et al. Early time restricted eating compared with daily
caloric restriction: A randomized trial of adults with obesity. Obesity
2022; 30:1027-38.
2) Estrada-DeLeon DB, et al. Association of prolonged nightly fasting
with cardiovascular, renal, inflammation, and nutritional status biomarkers in
community dwelling older adults. American Journal of Clinical Nutrition
2022; 115:1282-1289.
3) Liu D, et al. Calorie restriction with or without time restricted
eating in weight loss. New England Journal of Medicine 2022; 386:1495-504.